756 research outputs found
On stepdown control of the false discovery proportion
Consider the problem of testing multiple null hypotheses. A classical
approach to dealing with the multiplicity problem is to restrict attention to
procedures that control the familywise error rate (), the probability of
even one false rejection. However, if is large, control of the is so
stringent that the ability of a procedure which controls the to detect
false null hypotheses is limited. Consequently, it is desirable to consider
other measures of error control. We will consider methods based on control of
the false discovery proportion () defined by the number of false
rejections divided by the total number of rejections (defined to be 0 if there
are no rejections). The false discovery rate proposed by Benjamini and Hochberg
(1995) controls . Here, we construct methods such that, for any
and , . Based on -values of
individual tests, we consider stepdown procedures that control the ,
without imposing dependence assumptions on the joint distribution of the
-values. A greatly improved version of a method given in Lehmann and Romano
\citer10 is derived and generalized to provide a means by which any sequence of
nondecreasing constants can be rescaled to ensure control of the . We also
provide a stepdown procedure that controls the under a dependence
assumption.Comment: Published at http://dx.doi.org/10.1214/074921706000000383 in the IMS
Lecture Notes--Monograph Series
(http://www.imstat.org/publications/lecnotes.htm) by the Institute of
Mathematical Statistics (http://www.imstat.org
Stepup procedures for control of generalizations of the familywise error rate
Consider the multiple testing problem of testing null hypotheses
. A classical approach to dealing with the multiplicity problem is
to restrict attention to procedures that control the familywise error rate
(), the probability of even one false rejection. But if is
large, control of the is so stringent that the ability of a
procedure that controls the to detect false null hypotheses is
limited. It is therefore desirable to consider other measures of error control.
This article considers two generalizations of the . The first is
the , in which one is willing to tolerate or more false
rejections for some fixed . The second is based on the false discovery
proportion (), defined to be the number of false rejections
divided by the total number of rejections (and defined to be 0 if there are no
rejections). Benjamini and Hochberg [J. Roy. Statist. Soc. Ser. B 57 (1995)
289--300] proposed control of the false discovery rate (), by
which they meant that, for fixed , . Here,
we consider control of the in the sense that, for fixed
and , . Beginning with any
nondecreasing sequence of constants and -values for the individual tests, we
derive stepup procedures that control each of these two measures of error
control without imposing any assumptions on the dependence structure of the
-values. We use our results to point out a few interesting connections with
some closely related stepdown procedures. We then compare and contrast two
-controlling procedures obtained using our results with the
stepup procedure for control of the of Benjamini and Yekutieli
[Ann. Statist. 29 (2001) 1165--1188].Comment: Published at http://dx.doi.org/10.1214/009053606000000461 in the
Annals of Statistics (http://www.imstat.org/aos/) by the Institute of
Mathematical Statistics (http://www.imstat.org
On the uniform asymptotic validity of subsampling and the bootstrap
This paper provides conditions under which subsampling and the bootstrap can
be used to construct estimators of the quantiles of the distribution of a root
that behave well uniformly over a large class of distributions .
These results are then applied (i) to construct confidence regions that behave
well uniformly over in the sense that the coverage probability
tends to at least the nominal level uniformly over and (ii) to
construct tests that behave well uniformly over in the sense that
the size tends to no greater than the nominal level uniformly over
. Without these stronger notions of convergence, the asymptotic
approximations to the coverage probability or size may be poor, even in very
large samples. Specific applications include the multivariate mean, testing
moment inequalities, multiple testing, the empirical process and U-statistics.Comment: Published in at http://dx.doi.org/10.1214/12-AOS1051 the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
The AirWand: Design and Characterization of a Large-Workspace Haptic Device
Almost all commercially available haptic interfaces share a common pitfall, a small shoebox-sized workspace; these devices typically rely on rigid-link manipulator design concepts. In this paper we outline our design for a new kinesthetic haptic system that drastically increases the usable haptic workspace. We present a proof-of-concept prototype, along with our analysis of its capabilities. Our design uses optical tracking to sense the position of the device, and air jet actuation to generate forces. By combining these two technologies, we are able to detach our device from the ground, thus sidestepping many problems that have plagued traditional haptic devices including workspace size, friction, and inertia. We show that optical tracking and air jet actuation successfully enable kinesthetic haptic interaction with virtual environments. Given an appropriately large volume high-pressure air source, and a reasonably high speed tracking system, this design paradigm has many desirable qualities when compared to traditional haptic design schemes
Automatic Filter Design for Synthesis of Haptic Textures from Recorded Acceleration Data
Sliding a probe over a textured surface generates a rich collection of vibrations that one can easily use to create a mental model of the surface. Haptic virtual environments attempt to mimic these real interactions, but common haptic rendering techniques typically fail to reproduce the sensations that are encountered during texture exploration. Past approaches have focused on building a representation of textures using a priori ideas about surface properties. Instead, this paper describes a process of synthesizing probe-surface interactions from data recorded from real interactions. We explain how to apply the mathematical principles of Linear Predictive Coding (LPC) to develop a discrete transfer function that represents the acceleration response under specific probe-surface interaction conditions. We then use this predictive transfer function to generate unique acceleration signals of arbitrary length. In order to move between transfer functions from different probe-surface interaction conditions, we develop a method for interpolating the variables involved in the texture synthesis process. Finally, we compare the results of this process with real recorded acceleration signals, and we show that the two correlate strongly in the frequency domain
Optimal testing of multiple hypotheses with common effect direction
We present a theoretical basis for testing related endpoints. Typically, it is known how to construct tests of the individual hypotheses, but not how to combine them into a multiple test procedure that controls the familywise error rate. Using the closure method, we emphasize the role of consonant procedures, from an interpretive as well as a theoretical viewpoint. Surprisingly, even if each intersection test has an optimality property, the overall procedure obtained by applying closure to these tests may be inadmissible. We introduce a new procedure, which is consonant and has a maximin property under the normal model. The results are then applied to PROactive, a clinical trial designed to investigate the effectiveness of a glucose-lowering drug on macrovascular outcomes among patients with type 2 diabete
Dimensional Reduction of High-Frequencey Accelerations for Haptic Rendering
Haptics research has seen several recent efforts at understanding and recreating real vibrations to improve the quality of haptic feedback in both virtual environments and teleoperation. To simplify the modeling process and enable the use of single-axis actuators, these previous efforts have used just one axis of a three-dimensional vibration signal, even though the main vibration mechanoreceptors in the hand are know to detect vibrations in all directions. Furthermore, the fact that these mechanoreceptors are largely insensitive to the direction of high-frequency vibrations points to the existence of a transformation that can reduce three-dimensional high-frequency vibration signals to a one-dimensional signal without appreciable perceptual degradation. After formalizing the requirements for this transformation, this paper describes and compares several candidate methods of varying degrees of sophistication, culminating in a novel frequency-domain solution that performs very well on our chosen metrics
High Frequency Acceleration Feedback Significantly Increases the Realism of Haptically Rendered Textured Surfaces
Almost every physical interaction generates high frequency vibrations, especially if one of the objects is a rigid tool. Previous haptics research has hinted that the inclusion or exclusion of these signals plays a key role in the realism of haptically rendered surface textures, but this connection has not been formally investigated until now. This paper presents a human subject study that compares the performance of a variety of surface rendering algorithms for a master-slave teleoperation system; each controller provides the user with a different combination of position and acceleration feedback, and subjects compared the renderings with direct tool-mediated exploration of the real surface. We use analysis of variance to examine quantitative performance metrics and qualitative realism ratings across subjects. The results of this study show that algorithms that include high-frequency acceleration feedback in combination with position feedback achieve significantly higher realism ratings than traditional position feedback alone. Furthermore, we present a frequency-domain metric for quantifying a controller\u27s acceleration feedback performance; given a constant surface stiffness, the median of this metric across subjects was found to have a significant positive correlation with median realism rating
- …